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plain many of the diseases and conditions we Alzheimer's disease. She has also spoken on these The best way
are experiencing today in epidemic form. These topics in youtube videos as well as in workshops
include autism, Alzheimer’s, obesity, depres- hosted by the Weston A. Price Foundation. to minimize
sion, excessive violence, colitis, inflammatory glyphosate
bowel disease, heart disease and diabetes. I RefeRences exposure is to
now believe that, while several environmental 1. Altieri L, neri c, sacco R, curatolo P, Benvenuto A,
Muratori f, santocchi e, Bravaccio c, Lenti c, saccani M,
toxicants, including mercury, aluminum, lead, Rigardetto R, Gandione M, Urbani A, Persico AM. Urinary strictly adhere
fluoride, nitrates, insecticides and fungicides, p-cresol is elevated in small children with severe autism to a completely
spectrum disorder. Biomarkers 2011 May;16(3):252-60.
are likely implicated in autism, glyphosate 2. Axt, A. Autism viewed as a consequence of pineal gland organic diet.
may be the single most important factor in the malfunction. Farmakoterapia w Psychiatrii i Neurologii
1998, 98(1), 112-134.
autism epidemic. I believe this not only because 3. Baron-cohen, s. The extreme male brain theory of autism.
glyphosate usage has gone up in step with autism 4. Trends Cog. Sci. 2002, 6, 248-254.
Benbrook, c.M. Impacts of genetically engineered crops
rates, but also because many of the pathologies on pesticide use in the U.S. the first sixteen years. Environ-
associated with autism can be explained through 5. mental Sciences Europe 2012, 24:24.
Bernfield, M.; Gtte, M.; Park, P.W.; Reizes, O.; Fitzgerald,
glyphosate’s disruptive mechanisms. M.L.; Lincecum, J.; Zako, M. functions of cell surface
I also would argue that Alzheimer’s disease heparan sulfate proteoglycans. Annu. Rev. Biochem. 1999.
arises from similar pathologies as does autism, 6. 68:729777.
Blumberg, s.J.; Bramlett, M.D.; Kogan, M.D.; schieve,
and it might be characterized as “autism for the L.A.; Jones, J.R.; Lu, M.c. changes in Prevalence of
elderly.” Therefore, its recent alarming increases Parent-reported Autism spectrum Disorder in school-aged
U.s. children: 2007 to 20112012. national Health statistics
may also be due predominantly to glyphosate. Report no. 65, Mar. 20, 2013.
Glyphosate can also easily explain the obesi- 7. Bode, L.; Salvestrini, C.; Park, P.W.; 3 Li, J.-P.; Esko, J.D.;
Yamaguchi, Y.; Murch, s.; freeze, H.H. Heparan sulfate
ty epidemic and depression through its disruption and syndecan-1 are essential in maintaining murine and
of the supply of tryptophan, the sole precursor to human intestinal epithelial barrier function. J. Clin. Invest
Jan. 2008, 118(1), 229-238.
serotonin. I have shown how glyphosate disrupts 8. Breisch, s.T.; Zemlan, f.P.; Hoebel, B.G. Hyperphagia and
both sulfate synthesis and sulfate transport, and obesity following serotonin depletion by intraventricular
p-chlorphenylalanine. Science 1976, 192, 382-385.
my research has led me to believe that impaired 9. campbell McBride, n. Gut and Psychology Syndrome:
sulfate supply to all the tissues is a common Natural Treatment for Autism, Dyspraxia, A.D.D., Dyslexia,
A.D.H.D., Depression, Schizophrenia. Medinform Publish-
underlying pathology in most modern diseases. ing; Revised and enlarged edition, november 15, 2010.
The best way to minimize glyphosate 10. carman, J.A.; Vlieger, H.R.; Ver steeg, L.J.; sneller, V.e.;
Robinson, G.W.; Clinch-Jones, C.A.; Haynes, J.I.; Edwards,
exposure is to adhere strictly to a completely J.W. A long-term toxicology study on pigs fed a combined
organic diet. Most important is to avoid all the genetically modified (GM) soy and GM maize diet. Journal
of Organic Systems 2013, 8(1), 38-54.
Roundup-Ready GMO crops: corn, soy, sugar 11. carter-Kent, c.; Zein, n.n.; feldstein, A.e. cytokines in
beets, canola oil, and cottonseed oil, as well as the pathogenesis of fatty liver and disease progression to
steatohepatitis: implications for treatment. Am. J. Gastro-
wheat and sugar cane, due to desiccation prac- enterol. 2008, 103, 1036–1042.
tices. Any use of Roundup to kill weeds in lawn 12. Dawson, P. sulfate in fetal development. Semin. Cell Dev.
Biol. 2011, 22, 653-659.
maintenance should be abandoned. 13. de Bentzmann, s.; Plésiat, P. The Pseudomonas aeruginosa
opportunistic pathogen and human infections. Environ
Microbiol. 2011 Jul, 13(7), 1655-65.
Stephanie Seneff, PhD, is a Senior Research Sci- 14. Duke, S.O.; Vaughn. K.C.; Wauchope, R.D. Effects of
entist at MIT's Computer Science and Artificial glyphosate on uptake, translocation, and intracellular local-
ization of metal cations in soybean (Glycine max) seedlings.
Intelligence Laboratory. She has a Bachelor's Pestic. Biochem. Phys. 1985, 24, 384-394.
degree from MIT in biology with a minor in 15. Gamage, n.; Barnett, A.; Hempel, n.; Duggleby, R.G.;
Windmill, K.F.; Martin, J.L.; McManus, M.E. Human
food and nutrition, and her PhD from MIT is in sulfotransferases and their role in chemical metabolism.
computer science. Dr. Seneff is the first author of Toxicol. Sci. 2006, 90(1), 5-22.
several recently published papers on theories 16. Gasnier, c.; Dumont, c.; Benachour, n.; clair, e.; chagnon,
M.c.; séralini, G.e. Glyphosate-based herbicides are toxic
proposing that dietary deficiencies in critical nu- and endocrine disruptors in human cell lines. Toxicology
2009, 262, 184-191.
trients such as sulfur, taurine, zinc and choline, 17. Geiman, T.M.; Muegge, K. DnA methylation in early devel-
as well as insufficient sun exposure, compounded opment. Mol. Reprod. Dev. 2010, 77, 105-113.
by chronic exposure to environmental toxins can 18. Gorren, A.c.; Mayer, B. nitric-oxide synthase: A cyto-
chrome P450 family foster child. Biochim. Biophys. Acta
explain many modern diseases/conditions, such 2007, 1770, 432-445.
as autism, heart disease, obesity, arthritis and 19. Guarner, F.; Malagelada, J.-R. Gut flora in health and dis-
ease. The Lancet 2003, 360, 512-519.
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