Page 37 - Spring2020
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THE K FAMILY                              ACTIVATOR X                              Dr. Price’s
                Vitamin K comes in several forms:        Dr. Price’s Activator X is vitamin K  MK-
                                                                                        2
                                                      4. Dr. Price’s work in nutrition may be more   Activator X
            1.  Vitamin K  (phylloquinone) is found in  valuable to us today, as it is a source to refer  is vitamin
                         1
               plants and some animal sources; it is in-  to when the noise of synthetic supplementation   K  MK-4.
               volved in coagulation.                 drowns out the wisdom of our ancestors—the   2
            2.  Vitamin K  has side chains that contain  knowledge that all health starts with nutrient-
                         2
               from four to thirteen “isoprenoids,” rep-  dense, whole foods. As Price stated, “People
               resented as MK-4 to MK-13. MK means  of the past obtained a substance that modern
               menaquinone; the side chains are referred  generations  do  not have.” Yet increasingly
               to as short- and long-chain menaquinones  we are seeing statements in published papers
               (MKs). Vitamin K  MK-5 through MK-13  that “it is unlikely that MK-4 is an important
                               2
               are forms produced by bacterial synthesis.  dietary source of vitamin K in food supplies.”
            3.  Vitamin K  MK-4 is Dr. Price’s activator X  Such assertions, often by those with ties to the
                        2
               and is unique, in that it is the only form that  supplement industry, have led us to the defense
               is not the product of bacterial synthesis, but  of this key nutrient in food.
               comes from animal sources. (A synthetic     In his studies, Price found a fat-soluble vi-
               MK-4 is made from tobacco or geranium  tamin he called Activator X. He believed it was
               leaves.)                               a missing nutrient in our modern diet and that
            4.  Vitamin K  (menadione) is synthetic and  its absence could explain many of our modern
                         3
               water-soluble, and it has no side chain. The  diseases. He was able to heal caries, reduce oral
               FDA banned its use for human consump-  bacteria and cure other degenerative maladies in
               tion because of its high toxicity—although  his patients by giving butter oil, rich in activator
               it still is allowed in animal feed, usually as  X, along with cod liver oil. (Cod liver alone did
                                      3
               menadione sodium bisulfate  (a good reason  not work as well.)
               to eat grass-fed animal products).        Price wrote: “(a) [Activator X] plays an


                   O
                        CH                                        1.  Vitamin K  (phylloquinone) is found in plants and
                                                                              1
                          3
                                                                      some animal sources; it is involved in coagulation.
                                                        CH
                                                           3
                   o        CH       CH       CH      CH
                              3        3        3       3         2.  Vitamin K  MK-4 is Dr. Price’s activator X and is
                                                                               2
                                                                      unique, in that it is the only form that is not the
                    O                                                 product  of  bacterial  synthesis,  but  comes  from
                        CH                                            animal sources. (A synthetic MK-4 is made from
                          3
                                                                      tobacco and geranium leaves.)
                                                        CH
                                                          3
                   o        CH       CH       CH      CH
                                                        3
                                                                  3.  K  (menadione), is synthetic and water-soluble
                                       3
                              3
                                                3
                                                                       3
                                                                      and has no side chain. The FDA banned its use for
                   O                                                  human consumption because of its high toxicity—
                       CH                                             although it is still allowed in animal feed usually as
                         3
                                                                      menadione sodium bisulfate (a good reason to eat
                                                                      grass-fed products).
                   O
                                                                  4.   Menaquinone-7 (MK-7), is an example of a longer-
                    O                                                 chain menaquinone made by bacterial synthesis;
                                                                      MK-7 is found in natto and supplements.
                        CH 3
                                                                                    CH 3
                    O        CH 3    CH 3     CH 3     CH 3     CH 3     CH 3     CH 3

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