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histamine intolerance. However, due to the com-  Jill Cruz is a certified nutrition specialist with an M.S. in human nutri-
            plexity of MCAS, it often requires much deeper  tion. In 2008 she discovered the work of Weston A. Price and the power
            investigative work (it is challenging even to get  of using food as medicine, which sparked a passion for a new career in
            a diagnosis) and pharmaceutical interventions.  health and nutrition and for improving her and her family's health. She
                                                      has worked in the Hudson Valley Functional Medicine practice since
            IMPLEMENTING A                            2011. Jill believes that for people to reach their full health potential,
            LOW-HISTAMINE DIET                        they must acquire the skill of listening to and respecting their bodies
               The detailed low-histamine diet (next page)  and use their knowledge to take their health into their own hands. Jill
            is as strict as they come. Individuals who are not  works with a wide variety of conditions and specializes in healing diets
            sure about the extent to which histamine is af-  such as the ketogenic diet, the Patricia Kane membrane stabilizing diet
            fecting them might first want to try the less strict  and the SIBO diet. Her recommendations vary based on the individual's
            list described in the previous section, keeping  unique needs, circumstances, likes and dislikes, genetic predispositions
            in mind that many people do better with the  and financial and lifestyle requirements. For more information, visit
            stricter diet. We usually recommend following  bodywisefoodsmart.com/.
            the stricter diet for six weeks before deciding
            whether it has helped or not, because sometimes  REFERENCES
            it takes that long to reduce the body burden of   1.  Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr 2007;85(5):1185-
                                                        1196.
            histamine significantly. In most people, using   2.  MastCellAware. http://www.mastcellaware.com/index.html.
            the DAO enzyme and NeuroProtek will speed   3.  Molecular Immunopharmacology & Drug Discovery Laboratory. http://www.
                                                        mastcellmaster.com/index.php.
            up the process.                           4.  Armonk Integrative Medicine for Optimum Health. http://www.armonkmed.com/about/
               Low-histamine food lists on the Internet   dr-afrin/.
            may not be very reliable because they often   5.  Umbrellux™ DAO. https://www.umbrelluxdao.com/.
                                                      6.  NeuroProtek®. http://algonot.com/product/neuroprotek/.
            derive from the author’s subjective experiences.   7.  Manzotti G, Breda D, Di Gioacchino M, Burastero SE. Int J Immunopathol Pharmacol
                                                        2016;29(1):105-111.
            This can make the whole subject very confusing.   8.  Research: Dr. Theoharides at Tufts University. http://www.mastcellmaster.com/research.
            I recommend sticking to just one list and observ-  php.
            ing one’s body. Over time, it will become easier   9.  Study to investigate the effect of an oral diamine oxidase substitution (DAOsin) in histamine
                                                        intolerant patients on the low endogenous diamine oxidase serum activity. https://clinical
            to identify foods that are particularly problem-  trials.gov/ct2/show/NCT03298568.
            atic. It helps to start off more strictly to establish   10.  https://www.amazon.com/Caravaglio-Capers-Sicily-Pack-2/dp/B008SF2CZK.
            some sort of baseline, experimenting with more   11.  Histamine intolerance. www.low-histamine.com.
                                                      12.  Gibb JL. Is Food Making You Sick? The Strictly Low Histamine Diet. Brighton, Victoria:
            variety as one starts to feel better.       Leaves of Gold Press; 2014.








                                                    FOODS TO ENCOURAGE

              VEGETABLES: Add the following to dishes as much as possible: artichokes, basil, broccoli, celery, chives, cilantro, dill,
              garlic, onions (either cooked onions or spring onions in small amounts), oregano, parsley, rosemary, snap peas, wa-
              tercress, and ancho, serrano and chili peppers. These are all high in quercetin and other phytonutrients, which help
              reduce the body burden of histamine. Capers are particularly rich in quercetin, but one should use only salt-dried
              capers (not capers in vinegar).  Be sure to rinse the capers before using.
                                       10
              FRUIT: Apples and cranberries also are high in quercetin.

              GRAINS: Rice bran (especially from black rice) reduces histamine. Heirloom black rice can be found in health food
              stores (often called “forbidden rice”) or online.
                                                     11
              PEA SPROUTS: Although consumption of pea sprouts is optional, it is encouraged when possible. Pea sprouts can be
              used liberally as they are high in the DAO enzyme, which helps break down histamine. The easiest way to use them is
              to juice or blend them and drink with meals. Sprouting peas to get the highest amount of DAO takes about ten days.
              The best time to drink pea sprout juice is with any meal containing meat or fish.


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