Page 46 - Summer2018
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Constipation,       tion in up to one-third of children with autism.   children or adults, is “always a sign of deficient
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             whether in       Treatment can exacerbate the problems; for ex-  gut flora.”  As she elaborates in her book, Gut
                              ample, children suffering from both autism and  and Psychology Syndrome (GAPS):
             children or  constipation who receive medication (for either
                adults, is    their behavior or the constipation) are more   The beneficial bacteria that normally popu-
         “always a sign       likely to exhibit “rigid-compulsive behavior”   late the bowel play a crucial role in proper
                                                                           stool formation and elimination. The most
                              than their medication-free counterparts.
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            of deficient                                                   numerous species of friendly bacteria in a
              gut flora.”     THE BROADER DIGESTIVE CONTEXT                healthy bowel are Bifidobacteria and physi-
                                 Constipation, fundamentally, is a problem   ological strains of E. coli. These microbes
                              of digestion. Dr. Tom Cowan identifies three   produce a whole host of enzymes and other
                              principal factors underlying the epidemic of   active substances, whose action is essential
                              modern digestive disturbances.  First, he points   in proper stool formation. They stimulate
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                              out that “most of what we put in our mouths to-  the wall of the bowel to produce mucus for
                              day is not really food.” Industrial dairy products,   lubricating the stool and for passing it out
                              chemically treated vegetables, hormone- and   as soon as it is ready.
                              antibiotic-laced meats and MSG-laden packaged
                              concoctions are incapable of “calling forth the  CORRECTIVE MEASURES
                              forces of digestion” because the body does not   Conventional medicine typically recom-
                              recognize them as food and cannot properly  mends short-term interventions such bulking
                              break them down.                         agents, stool softeners and osmotic, stimulant or
                                 Second, the glands and organs that are sup-  combination laxatives, but these often produce
                              posed to supply pancreatic and liver enzymes  “mixed or even unsatisfactory results” despite
                              for digestion often fail to do so in adequate  “frequent interventions.”  One longitudinal
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                              amounts, in part due to the lack of dietary trace  study found that 89 percent of patients with con-
                              minerals that are key molecular building blocks  stipation reported no change in their condition
                              of digestive enzymes. Magnesium, for example,  after a year.  Occasionally, clinicians admit that
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                              is a component of over three hundred enzymes  laxatives can provoke “abdominal cramping,
                              in the human body,  including those needed for  distension, and vomiting, without producing
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                              digestion, and low magnesium intake is associ-  bowel movements”; in these cases, the patients
                              ated with increased prevalence of constipation.   apparently are out of luck and considered “non-
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                                 The third contributing factor—one that has  manageable.”  Among individuals who seek
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                              achieved a considerable degree of awareness in  care for constipation, many are dissatisfied with
                              both the lay press and the scientific literature—  the currently available treatment options. 33
                              is that many of us have a “polluted” bowel eco-  Probiotic supplements have become one
                              system that lacks the beneficial microorganisms  increasingly trendy response to address the
                              needed to support digestion. As Cowan notes,  gut microbiome depletion that contributes to
                              the small and large intestine ecosystem is “full  constipation. Although the American College
                              of a wide variety of interdependent organisms”  of Gastroenterology remains unwilling to en-
                              that “interact with each other, …with their host,  dorse probiotics for constipation,  many other
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                              and…with the larger world around them.”   researchers and clinicians point to promising re-
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                              In this scenario, “dietary constituents and the  sults from both animal and human studies, even
                              colonic microbiota interact to generate biologi-  if the supplements’ mechanisms of action on
                              cally active molecules that influence gut motility  gut motility and constipation remain unclear.
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                              and secretion.”  When the gut microbiota are  Research and commercial interest in probiotics
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                              imbalanced or dysfunctional, this “may contrib-  is at an all-time high. Plugging the search terms
                              ute to aberrant gut motility and, consequently,  “probiotics” and “constipation” into PubMed's
                              symptoms of constipation.”               search engine pulls up three hundred and sixty-
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                                 In plainer terms, Dr. Natasha Campbell-  eight articles spanning the twenty years from
                              McBride explains that constipation, whether in  1998 to 2018; over four thousand six hundred

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