Why Do I Still Have Thyroid Symptoms by Datis Kharrazian |
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| Written by Shannon Nash |
| June 28 2010 |
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“In the U.S., autoimmune disease accounts for approximately 90 percent of adult hypothyroidism, mostly due to Hashimoto’s” (page 23). “Although iodine deficiency is the most common cause of hypothyroidism for most of the world’s population, in the United States and other westernized countries, Hashimoto’s accounts for the majority of cases of hypothyroidism” (page 27). Datis Kharrazian clearly establishes the fact that Hashimoto’s disease is not a thyroid issue per se but rather an autoimmune disease and therefore, like other autoimmune disorders, can only be treated by balancing the immune system. If there are 27 million Americans with malfunctioning thyroids, as some experts estimate, then there must also be a huge number of undiagnosed Hashimoto’s patients in the U.S. Most practitioners fail to test for Hashimoto’s in a hypothyroid patient because they do not change their treatment plan for Hashimoto’s. Instead of treating the immune system, conventional practitioners will treat the thyroid gland in a Hashimoto’s patient. People suffering from hypothyroidism will greatly benefit from reading Why Do I Still Have Thyroid Symptoms When My Lab Tests Are Normal? In the first part of the book, Kharrazian explains the relationship between Hashimoto’s disease, the immune system, the thyroid gland, and gluten. Sadly, for people with Hashimoto’s, gluten must be avoided for life. The gliadin portion of the gluten causes the immune system to flare up and attack not only the gluten in the blood stream but also the thyroid gland, due to the similarity of gliadin and peptide fragments associated with the thyroid gland. A leaky gut is to blame for gluten getting in the bloodstream in the first place, but once the gluten-sensitive genes are turned on, they cannot be turned off, and therefore gluten must be avoided for life. Amazingly, “the immune response to gluten can last up to six months each time it is ingested.” Each time a person with Hashimoto’s consumes gluten, he risks a possible six-month attack on his thyroid gland. Using emulsified vitamin D, glutathione cream and S.O.D. (superoxide dismutase), Kharrazian has had much success in the first step of bringing balance to the immune system. Not only is vitamin D a powerful immune modulator, but “90 percent of people with an autoimmune thyroid disease have a genetic defect that affects their ability to process vitamin D.” Although their blood tests may show adequate levels of D, the vitamin D deficiency is at the cellular level. Therefore, in his practice Kharrazian likes to see autoimmune thyroid patients in the high normal end of vitamin D status. Vitamin D also supports the T-regulatory cells, which begin to malfunction in an autoimmune attack. As their name suggests, when T-regulatory cells malfunction, the regulation of the immune attack goes awry. Tissue damage occurs when the incorrect amounts of T-helper and T-suppressor cells are called for by the weary T-regulatory cells. Using emulsified vitamin D, Kharrazian reestablishes proper function of the T-regulatory cells. Taming the dominant side of the immune system is the second step in balancing the immune system. The two major parts of the immune system are the TH-1 pathway, which produces an immediate response and the TH-2 pathway, which produces a delayed response. Using a lab test, Kharrazian measures the percentages of each type of cytokine to determine which side of the immune system is dominant. He lists in his book nutritional compounds that will stimulate each side (TH-1 or TH-2) of the immune system. Kharrazian tames the dominant side by giving supplements that will strengthen the weaker side. For instance, if a person is TH-1 dominant, as 90 percent of those with Hashimoto’s are, then they would consume herbs such as astragalus and echinacea, which stimulate the TH-2 pathway. Since not all autoimmune responses are due to an imbalance of the two sides, Kharrazian also gives direction on how to treat an immune response when caused by an antigen or hapten, such as those created by chronic infection, pesticides or heavy metals. The second half of the book concisely covers the six patterns of hypothyroidism that are not caused by Hashimoto’s, how to discover them from a blood test, and why only one can be remedied with thyroid medication. Kharrazian devotes a chapter to each of the following cofactors of thyroid health: blood sugar, digestion, adrenal glands, use of hormone pills that destroy thyroid health, and the brain. At the end of each chapter, the reader will find recommended supplements that can strengthen or stabilize each possible problem area. Kharrazian has put together a very comprehensive guide to understanding the complicated and varied path toward reestablishing thyroid health including improving adrenal, blood sugar and hormonal health. I give this a hearty thumbs up as an excellent reference book with two small caveats. The first is that Kharrazian promotes using emulsified D and fish oil (for EPA and DHA) instead of cod liver oil, which he says, would not supply enough vitamin D without too much EPA and DHA. My opinion is that one could work with a practitioner and use cod liver oil in conjunction with emulsified D to obtain therapeutic levels of D. Kharrazian notes that vitamin A is a modulator to both sides of the immune system as well as “a critical nutrient for thyroid activity,” but fails to make the connection that cod liver oil is an excellent source of vitamin A. Finally he points out strong anecdotal evidence that people with Hashimoto’s do best on a casein free (dairy free) diet. The issue I find with advice to avoid all dairy is that rarely is any distinction made between raw, cultured, and pasteurized dairy; therefore, I feel that the dairy free recommendation may need to be explored on an individual basis. This article appeared in Wise Traditions in Food, Farming and the Healing Arts, the quarterly magazine of the Weston A. Price Foundation, Summer 2010.
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written by concerned, Feb 29 2012
Kharrazian's vitamin D with cod liver oil contains Genistein from soy which has gotten a lot of bad press by the WPF website for being damaging to thyroid health which makes me wonder why its in there. Also the Apex Oxi-cell cream he formulated for Hashi patients contains Fluoride as Fluoric Acid which is also known to suppress the thyroid. The no dairy, egg, gluten, soy, high glycemic fruit, lectin (including nuts and beans), nightshade, alcohol, and caffeine diet in the book seems to leave someone with almost nothing to eat besides meat and veggies and low carb fruits. A low carb diet high in muscle meats suppresses thyroid function and stresses the adrenals. I find the whole immune system imbalance thing fascinating and think that it would be great if taking herbs to balance the immune system work to fix autoimmune issues which are so prevalent now. What a simple fix if it really works! I do think its weird that the products he created for his protocol contain substances that inhibit thyroid function as well as the "healing diet" he recommends. Also, I tried the Oxi-cell cream and got a horrible rash from it. Tried supplementing with an emulsified D(just D no Genistein) along with my cod liver oil with no benefits. Also took his glutathione recycler supplement and noticed no change. Also followed the diet with no positive changes which is frustrating because the food was so monotonous. My digestion also felt much worse on this strict diet and my teeth began to decay. I have not had my immune system tested and have not tried the herbs to boost the weaker immune branch yet, I don't know if I will after my experience with the other products. I just think there are a great deal of expensive tests and supplements and very strict diets, and a lot of of it is pointless or overkill. I have had better luck following Ray Peat's guidelines with sugar, gelatin, dairy, coconut oil, coffee and fruit and avoidance of PUFAs and its far more enjoyable to eat this way. On Datis' diet and protocol I had lower temperatures and pulse and felt more and more lethargic until I was pretty much bedridden, severe brain fog and forgetfulness, exhausted, dizzy, depressed and horrible PMS. With the Peat diet without supplements I continue to feel better and better. Check out Josh Rubin's youtube on Hashimoto's for another perspective http://www.youtube.com/watch?v...ature=plcp
incorrect example of stimulators for TH1/TH2 dominance
written by Eileen, Dec 06 2010
I believe you may have mixed up the recommended stimulants for the TH1 vs. TH2 dominance according to the info in Dr. K's book.
"It is well documented in clinical research that Th1 stimulants are Echinacea, maitake mushrooms and golden seal to name a few. Th2 stimulators are caffeine, green tea, and grape seed extract. So in the example I gave in the previous slide, if a patient with an under functioning thyroid is TH1 dominant, then I would prescribe supplements containing caffeine, green tea, and grape seed extract to stimulate the TH2 side to regain balance. If they were TH2 dominant, then Echinacea, mushrooms, and golden seal would balance out their immune system." (http://www.medhelp.org/user_jo...2-dominant) The example you gave in your review says the opposite.
Good summary
written by John, Jul 08 2010
I like your write up and would add that goat dairy may be another overlooked option. I don't recall it being mentioned in the book.
I would add this book is intended for the health care professional. Dr.K is now on a campaign to train health care providers in his approach to Hashimotos and thyroid related issues. Some of the areas covered do get technical and complicated. He often leaves out certain dosing details for many of the recommended supplements as they need to be individualized case by case. Nonetheless this is still an excellent book for the patient who wants to be better informed and can find a knowledgeable practitioner to work with. Unfortunately most MD's have not embraced this or similar approaches and will leave you untreated or worse, give an incorrect diagnosis.
Corrections written by Elaine, Jul 02 2010
Hi, one error here: "For instance, if a person is TH-1 dominant, as 90 percent of those with Hashimoto’s are, then they would consume herbs such as astragalus and echinacea, which stimulate the TH-2 pathway."
Astragalus and echinacea stimulate TH-1, not TH-2. Also I know he uses emulsified vitamin D in a cod liver oil base to get the therapeutic doses of D often needed, so he still uses CLO, just with a D boost. Write comment -
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| Last Updated on Wednesday, April 04 2012 08:24 |




